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perineuronal nets pnn  (Vector Laboratories)


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    Vector Laboratories perineuronal nets pnn
    Methods use for immunofluorescence marker quantification and analysis
    Perineuronal Nets Pnn, supplied by Vector Laboratories, used in various techniques. Bioz Stars score: 96/100, based on 186 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/perineuronal nets pnn/product/Vector Laboratories
    Average 96 stars, based on 186 article reviews
    perineuronal nets pnn - by Bioz Stars, 2026-03
    96/100 stars

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    1) Product Images from "Cognitively impaired aged Octodon degus recapitulate major neuropathological features of sporadic Alzheimer’s disease"

    Article Title: Cognitively impaired aged Octodon degus recapitulate major neuropathological features of sporadic Alzheimer’s disease

    Journal: Acta Neuropathologica Communications

    doi: 10.1186/s40478-022-01481-x

    Methods use for immunofluorescence marker quantification and analysis
    Figure Legend Snippet: Methods use for immunofluorescence marker quantification and analysis

    Techniques Used: Immunofluorescence, Marker, Activity Assay

    Increased perineuronal nets signal coupled with an increase of PV-positive interneurons in the AD-like aged degu brain. Confocal microscopic views of degu coronal brain sections are aligned as indicated and show focused views of perineuronal nets (PNN) (green), parvalbumin (PV) interneurons (red), and neuronal nuclei (NeuN, blue) in entorhinal cortex (EC, a and d ), hippocampal CA2 and CA3 (Hippo, b and e ), and thalamic reticular nucleus (TRN, c and f ). g – l Quantification shows significantly increased counts of PNN(+)-neurons per mm 2 ( g ) and PV(+)-neurons per mm 2 ( h ) in EC ( p = 0.0022 and p 0.0260, respectively) in AD-like degu brains compared to Non-AD controls, along with similar trends for hippocampal CA3/CA2 ( p = 0.0931 for PNN; p = 0.3636 for PV) and TRN ( p = 0.3939 for PNN; p = 0.5887 for PV). Error bars represent SEM; * p < 0.05, ** p < 0.01, n = 6 degus in AD-like and Non-AD groups, n = 3 for male AD-like and female AD-like groups
    Figure Legend Snippet: Increased perineuronal nets signal coupled with an increase of PV-positive interneurons in the AD-like aged degu brain. Confocal microscopic views of degu coronal brain sections are aligned as indicated and show focused views of perineuronal nets (PNN) (green), parvalbumin (PV) interneurons (red), and neuronal nuclei (NeuN, blue) in entorhinal cortex (EC, a and d ), hippocampal CA2 and CA3 (Hippo, b and e ), and thalamic reticular nucleus (TRN, c and f ). g – l Quantification shows significantly increased counts of PNN(+)-neurons per mm 2 ( g ) and PV(+)-neurons per mm 2 ( h ) in EC ( p = 0.0022 and p 0.0260, respectively) in AD-like degu brains compared to Non-AD controls, along with similar trends for hippocampal CA3/CA2 ( p = 0.0931 for PNN; p = 0.3636 for PV) and TRN ( p = 0.3939 for PNN; p = 0.5887 for PV). Error bars represent SEM; * p < 0.05, ** p < 0.01, n = 6 degus in AD-like and Non-AD groups, n = 3 for male AD-like and female AD-like groups

    Techniques Used:



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    Image Search Results


    Methods use for immunofluorescence marker quantification and analysis

    Journal: Acta Neuropathologica Communications

    Article Title: Cognitively impaired aged Octodon degus recapitulate major neuropathological features of sporadic Alzheimer’s disease

    doi: 10.1186/s40478-022-01481-x

    Figure Lengend Snippet: Methods use for immunofluorescence marker quantification and analysis

    Article Snippet: Perineuronal nets (PNN) were immunostained using biotinylated Wisteria floribunda agglutinin (WFA; Vector Laboratories, cat# B-1355-2).

    Techniques: Immunofluorescence, Marker, Activity Assay

    Increased perineuronal nets signal coupled with an increase of PV-positive interneurons in the AD-like aged degu brain. Confocal microscopic views of degu coronal brain sections are aligned as indicated and show focused views of perineuronal nets (PNN) (green), parvalbumin (PV) interneurons (red), and neuronal nuclei (NeuN, blue) in entorhinal cortex (EC, a and d ), hippocampal CA2 and CA3 (Hippo, b and e ), and thalamic reticular nucleus (TRN, c and f ). g – l Quantification shows significantly increased counts of PNN(+)-neurons per mm 2 ( g ) and PV(+)-neurons per mm 2 ( h ) in EC ( p = 0.0022 and p 0.0260, respectively) in AD-like degu brains compared to Non-AD controls, along with similar trends for hippocampal CA3/CA2 ( p = 0.0931 for PNN; p = 0.3636 for PV) and TRN ( p = 0.3939 for PNN; p = 0.5887 for PV). Error bars represent SEM; * p < 0.05, ** p < 0.01, n = 6 degus in AD-like and Non-AD groups, n = 3 for male AD-like and female AD-like groups

    Journal: Acta Neuropathologica Communications

    Article Title: Cognitively impaired aged Octodon degus recapitulate major neuropathological features of sporadic Alzheimer’s disease

    doi: 10.1186/s40478-022-01481-x

    Figure Lengend Snippet: Increased perineuronal nets signal coupled with an increase of PV-positive interneurons in the AD-like aged degu brain. Confocal microscopic views of degu coronal brain sections are aligned as indicated and show focused views of perineuronal nets (PNN) (green), parvalbumin (PV) interneurons (red), and neuronal nuclei (NeuN, blue) in entorhinal cortex (EC, a and d ), hippocampal CA2 and CA3 (Hippo, b and e ), and thalamic reticular nucleus (TRN, c and f ). g – l Quantification shows significantly increased counts of PNN(+)-neurons per mm 2 ( g ) and PV(+)-neurons per mm 2 ( h ) in EC ( p = 0.0022 and p 0.0260, respectively) in AD-like degu brains compared to Non-AD controls, along with similar trends for hippocampal CA3/CA2 ( p = 0.0931 for PNN; p = 0.3636 for PV) and TRN ( p = 0.3939 for PNN; p = 0.5887 for PV). Error bars represent SEM; * p < 0.05, ** p < 0.01, n = 6 degus in AD-like and Non-AD groups, n = 3 for male AD-like and female AD-like groups

    Article Snippet: Perineuronal nets (PNN) were immunostained using biotinylated Wisteria floribunda agglutinin (WFA; Vector Laboratories, cat# B-1355-2).

    Techniques: